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Managing Lab SOPs as a Living Knowledge Base

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Our protocols keep changing. How do we prevent chaos while still improving them?

Laboratory methods are not static documents. They evolve.

  • Incubation times are optimized
  • Reagents are replaced
  • Equipment changes
  • Troubleshooting knowledge accumulates
  • Students contribute improvements

Over time, a single SOP may exist in multiple slightly different versions across computers, emails, and printed folders.

This guide demonstrates how a laboratory can transform its SOP collection into a living knowledge base using Git.

Instead of treating protocols as isolated documents, we treat them as:

  • Versioned knowledge
  • Collaborative artefacts
  • Traceable scientific infrastructure

Git is not the goal.
It is the mechanism that enables structured SOP governance.

Learning Goals

After this guide, you will understand how to:

  • Organize SOPs as Markdown files
  • Manage them in a Git repository
  • Track procedural evolution
  • Coordinate multi-person editing
  • Freeze protocol versions for publications
  • Establish basic governance rules

Scientific knowledge evolves.
Your protocol system should evolve with it.